Table 1 |
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Leishmania expressing reporter gene whose capacity to be used in vitro for drug screening procedure has been determined |
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Species |
Reporter gene |
Expression |
Ref |
|
|
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|
L. donovani/L. donovaniR |
Firefly luciferase |
Episomal |
16 |
|
L. amazonensis |
Firefly luciferase |
Integration |
17 |
|
L. infantum/L. infantum RSbIII1 |
Firefly luciferase |
Episomal |
14 |
|
L. donovani |
GFP |
Episomal |
7 |
|
L. donovani R2 |
10 |
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|
L. amazonensis |
β-Lactamase |
Episomal |
12 |
|
L. major |
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|
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1 in vitro selected trivalent antimony resistant L. infantum. 2 Field isolates of L. donovani resistant to pentavalent antimony. |
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Monte-Alegre et al. Kinetoplastid Biology and Disease 2006 5:6 doi:10.1186/1475-9292-5-6 |
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