Table 1

Leishmania expressing reporter gene whose capacity to be used in vitro for drug screening procedure has been determined

Species
Reporter gene
Expression
Ref

L. donovani/L. donovaniR
Firefly luciferase
Episomal
16
L. amazonensis
Firefly luciferase
Integration
17
L. infantum/L. infantum RSbIII1
Firefly luciferase
Episomal
14
L. donovani
GFP
Episomal
7
L. donovani R2


10
L. amazonensis
β-Lactamase
Episomal
12
L. major




1 in vitro selected trivalent antimony resistant L. infantum. 2 Field isolates of L. donovani resistant to pentavalent antimony.

Monte-Alegre et al. Kinetoplastid Biology and Disease 2006 5:6   doi:10.1186/1475-9292-5-6