Table 1

Leishmania expressing reporter gene whose capacity to be used in vitro for drug screening procedure has been determined

Species

Reporter gene

Expression

Ref


L. donovani/L. donovaniR

Firefly luciferase

Episomal

16

L. amazonensis

Firefly luciferase

Integration

17

L. infantum/L. infantum RSbIII1

Firefly luciferase

Episomal

14

L. donovani

GFP

Episomal

7

L. donovani R2

10

L. amazonensis

β-Lactamase

Episomal

12

L. major


1 in vitro selected trivalent antimony resistant L. infantum. 2 Field isolates of L. donovani resistant to pentavalent antimony.

Monte-Alegre et al. Kinetoplastid Biology and Disease 2006 5:6   doi:10.1186/1475-9292-5-6

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